In the present study the effect of ethanolic extract of Buchanania lanzan bark (EEBL) was studied against toxicity induced by Naja
kaouthia snake venom by various in vivo and in vitro studies. The EEBL was evaluated for neutralization of lethality, myotoxocity,
Phospholipase A2 activity and Human RBC lysis produced by Naja kaouthia snake venom. The EEBL 200mg/kg and 400mg/kg
significantly neutralized the lethality produced at different concentration of snake venom. Myotoxicity also decreased up to a
significant level characterized by decline in creatine phosphokinase (CPK) level. In vitro models for assessing hemolytic activity were
found to be significantly decreased in the presence of EEBL. Both direct and indirect hemolytic study was performed at various
concentration of EEBL. More than 50% of hemolysis was significantly neutralized by the extract. Results showed significant
neutralization of toxicity produced by N. kaouthia snake venom. However, further study is needed to determine the mechanism of
action and to find out the active components responsible for its antivenom activity.