The purpose of this report is to present the case of a patient wherein revascularization of the necrotic infected pulp space of an
immature permanent maxillary central incisor tooth was induced in vivo by stimulation of a blood clot from the periapical tissues into
the canal space. This was achieved after disinfecting the canal space with a topical antibiotic paste followed by inducing a blood clot
scaffold from the periapical tissues. This treatment approach offers great potential to avoid the need for traditional apexification with
calcium hydroxide or the need to achieve an artificial apical barrier with mineral trioxide aggregate. Furthermore, this treatment
approach can help rescue infected immature teeth by physiologically strengthening the root walls.