RE-DESIGNED, RE-ENGINEERED AND RE-INVENTED: THE CURIOUS LIFE OF THE BIOMARKER

Early detection of any diseases plays a important role in successful treatment. Early diagnosis and treatment reduces the severity and
possible complications of the disease activity. Medical researchers are devoted to finding molecular disease biomarkers that reveal a
hidden risk, before the disease becomes complicated. Saliva and other body fluids, containing a highly complex mixture of substances,
rapidly gaining popularity as a diagnostic tool. Periodontal disease is a multifacorial disease of the oral cavity comprising a group of
inflammatory conditions affecting the supporting structures of the dentition. Saliva and other body fluids like GCF as a mirror of oral
and systemic health, is a valuable source for clinically relevant information because it contains biomarkers specific for periodontal
diseases. This review highlights the various potentials of saliva as a diagnostic biomarker for periodontal diseases