The present investigation is part of continuing programme related to the phytochemical screening of Andrographis Paniculata Nees
(Kalmegh) and effect of antibiotics mixing with the Andrographis Paniculata Nees (herbal extracts) their enhanced potential on
microbes. In the world the local plants used in Ancient Indian Medicine, Ayurveda, Siddha and Yunani, in several countries including
India several plant species are administered orally to control the various diseases. Some of these plants have been pharmacologically
provided to be of some value and may be a popular remedy for the treatment of disease.
From the very beginning of human existence, man has familiarized himself with medicinal plants and used them in a variety of ways
throughout the ages. In search of food and to cope successfully with human suffering, primitive man began to distinguish those plants
suitable for nutritional purpose from others with definitive pharmacological action. This relationship has grown between plants and
man, and many plants came to be used as drugs. The growth of knowledge to cure disease continues at an accelerating pace, and
number of new plant-derived drugs increase likewise. Herbal medicine is currently experiencing a revival in Western society along
with other complementary therapies such as traditional Chinese Medicines, Osteopathy and Homeopathy. In this context, the present
study is the first milestone with particular emphasis on the application of Andrographis Paniculata Nees (kalmegh) the medicinal plant
and their effect in mixing with antibiotics for their better formulation and controlling the various diseases in near future.