RP-HPLC AND UV QUANTIFICATION OF ANTIRETROVIRAL DRUGS IN FIXED DOSAGE FORMS

A simple and improved liquid chromatographic method with reduced run time and a cost effective UV spectrophotometric
have been developed for the quantitation of antiretroviral drugs in a combined dosage form three drugs. All the analytical
parameters were determined as per ICH Q2B guidelines. Both the methods displayed good linearity, reproducibility and precisio
spectral or chromatographic interference were observed. The validated methods are reliable and can be suitably applied for th
quality control analysis in the estimation of commercial formulations