Introduction: Autologous osteoblast implantation is a newer technique employed in osteogenesis and has turned out to be a great
boon in bone augmentation. It is a unique option available in bone augmentation when donor site has a limitation to offer the required
volume. This article throws light on the fact that somatic cells can be harvested from a person, multiplied outside his body using bioengineering
principles and technologies and later introduced into a tissue defect. Thus tissue engineering is poised to have a major
impact on cranio-maxillofacial surgery in near future.
Materials and Methods: We are reporting a case in which cyst was enucleated and the cavity was filled with autogenous osteoblast
derived from anterior iliac crest bone marrow using Jamshidi needle – 11 Gz & 10 cm (care fusion) which was collected in a bottle
with Dulbecco’s Modified Eagle Medium (DMEM) and was harvested for 4 weeks after which it was implanted in the bony cavity.
Results: As per the serial radiographs taken the result was excellent and the bony cavity was adequately filled with woven bone.
Conclusion: Thus, Autologous osteoblast implantation, although a bit expensive, is a reliable technique for reconstruction of bony